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No microscopic changes were observed in the testes of rats from Simvastatin generic Pills study. The clinical significance of these findings is unclear. There are no adequate and well-controlled studies of use with ZOCOR during pregnancy; however, there are rare reports of congenital anomalies in infants exposed to statins in utero.

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Animal reproduction studies of simvastatin in rats and rabbits showed no evidence of teratogenicity. There are rare reports of congenital anomalies following intrauterine exposure to statins. However, the study was only able to exclude a 3- to 4-fold increased risk of congenital anomalies over the background rate. Women of childbearing potential, who require treatment with ZOCOR for a lipid disorder, should be Simvastatin generic Pills to use effective contraception. Nursing Mothers It is not known whether simvastatin is excreted in Simvastatin generic Pills milk. Pediatric Use Safety and effectiveness of simvastatin in patients 10-17 years of age with heterozygous familial hypercholesterolemia have been evaluated in a controlled clinical trial in adolescent boys and in girls who were at least 1 year post-menarche.

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Patients treated with simvastatin had an adverse reaction profile similar to that of patients treated with placebo, Simvastatin Generic Pills. Doses greater than 40 mg have not been studied in this population. Simvastatin has not been studied in patients younger than 10 years of age, nor in pre-menarchal girls. Lipid-lowering efficacy was at Simvastatin generic Pills as great in elderly patients compared with younger patients, and ZOCOR significantly reduced total mortality and CHD mortality in elderly patients with a history of CHD. The relative risk reductions of CHD death, non-fatal MI, coronary and non-coronary revascularization procedures, and stroke were similar in older and younger patients.

There were no overall differences in safety between older and Simvastatin generic Pills patients in Simvastatin generic Pills 4S or HPS. No specific diagnostic signs were observed in rodents. At these doses the only signs seen in dogs were emesis and mucoid stools. All patients recovered without sequelae. Supportive measures should be taken in the event of an overdose.

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The dialyzability of simvastatin and its metabolites in man is not Simvastatin generic Pills at Simvastatin generic Pills. Women who are pregnant or may become pregnant. Simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism underactive thyroid. FDA pregnancy category X.

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This medicine can harm an unborn baby or cause birth defects. Do not take simvastatin if you are Simvastatin generic Pills. Stop Simvastatin generic Pills this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking this medicine. Simvastatin may pass into breast milk and could harm a nursing baby.

Do not breast-feed while you are Simvastatin generic Pills this medicine. How should I take simvastatin? Take simvastatin exactly as prescribed. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed.

Taking too much of this medication may cause Simvastatin generic Pills or life-threatening side effects. Simvastatin is usually taken at bedtime or with an evening meal. If you take simvastatin more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results, Simvastatin Generic Pills.

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While using simvastatin, you may need frequent blood tests at your doctor’s office. You may need to woojintop.smart-apps.co.kr simvastatin on a Simvastatin generic Pills basis for the treatment of high cholesterol. You may need to stop using this medicine for a Simvastatin generic Pills time if you have surgery or a medical emergency.

Do not stop taking this medicine unless your doctor tells you to. Simvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

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